NAD+-dependent HDAC inhibitor stimulates Monascus pigment production but inhibit citrinin
نویسندگان
چکیده
منابع مشابه
EFFECT OF DISSOLVED OXYGEN CONCENTRATION ON RED PIGMENT AND CITRININ PRODUCTION BY Monascus purpureus ATCC 36928
The present study investigated the effects of agitation speed, N (200, 500, 600 or 700 rpm), and dissolved oxygen concentration, C (120, >70, 70, 60, 10 or 10%), on red pigment and citrinin production by Monascus purpureus ATCC 36928, cultivated in liquid medium by a batch process. The gas flow rate was the same for all runs with C controlled by means of the incoming gas composition control (ai...
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Exposure of the fungus Chaetomium cancroideum to an NAD(+)-dependent HDAC inhibitor, nicotinamide, enhanced the production of aromatic and branched aliphatic polyketides, which allowed us to isolate new secondary metabolites, chaetophenol G and cancrolides A and B. Their structures were determined using spectroscopic analyses, and their absolute configuration was elucidated by electronic circul...
متن کاملBiopigments from Monascus: Strains Selection, Citrinin Production and Color Stability
Fungi form the genus Monascus are a promising source for natural color additives. However, before effectively applying Monascus to foods, it is important to select strains which produce large amounts of biopigments but little or no citrinin, a mycotoxin usually also produced by these fungi. Also, color stability of these pigments should be properly investigated. In order to compare Monascus str...
متن کاملHDAC inhibitor misprocesses bantam oncomiRNA, but stimulates hid induced apoptotic pathway
Apoptosis or programmed cell death is critical for embryogenesis and tissue homeostasis. Uncontrolled apoptosis leads to different human disorders including immunodeficiency, autoimmune disorder and cancer. Several small molecules that control apoptosis have been identified. Here, we have shown the functional role of triazole derivative (DCPTN-PT) that acts as a potent HDAC inhibitor and mis-ex...
متن کاملComparative Study of Monascus Sanguineus and Monascus Purpureus as Potential Sources for Red Pigment Production
Monascus spp. namely Monascus sanguineus was isolated from pomegranate (Punica granatum). In this study, the isolated M. sanguineus was compared with M. purpureus MTCC410 procured from MTCC Chandigarh, India for optimising the red pigment yield. It was observed that both strains had produced maximum red pigment on the 16 day of incubation (21.9 CVU/ml for M. sanguineus & 16.9 CVU/ml for M. purp...
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ژورنال
عنوان ژورنال: AMB Express
سال: 2017
ISSN: 2191-0855
DOI: 10.1186/s13568-017-0467-1